2-(2-METHOXY PHENOXY) ETHYL AMINE (BASE)

Product Description

22Methoxyphenoxyethylamine Base is the freebase form of the compound differing from the hydrochloride salt by the absence of the protonated amine and chloride counterion Below is a detailed description

 Chemical Information

 Chemical Name 22Methoxyphenoxyethylamine Base  

 Chemical Formula C9H13NO2  

 Molecular Weight 16721 gmol  

 Structure  

   Phenoxy Group A benzene ring substituted with a methoxy group OCH3 at the 2nd position and linked via an ether bond O to the ethyl chain  

   Amino Group NH2 Attached to the terminal carbon of the ethyl chain

 Physical Properties

 Appearance A clear liquid or paleyellow solid depending on temperature and purity  

 Melting Point Usually lower than the hydrochloride salt due to the absence of ionic interactions  

 Boiling Point Approximately 260280C  

 Solubility  

   Soluble in organic solvents like ethanol methanol or acetone  

   Slightly soluble in water compared to its hydrochloride salt

 Applications

1 Pharmaceutical Intermediate  

    Used in the synthesis of therapeutic agents such as betablockers and adrenergic receptor modulators  

    Key precursor in the production of antihypertensive and antiarrhythmic drugs

2 Organic Synthesis  

    Versatile intermediate for creating more complex molecules in research and chemical industries  

    Phenoxy and amine groups make it amenable to further functionalization

3 Material Science  

    Used as a building block for creating polymers or advanced materials with specific properties

 Safety and Handling

 Hazards  

   Flammable keep away from heat and open flames  

   May cause irritation to the skin eyes and respiratory tract Avoid prolonged exposure  

 Handling  

   Use standard laboratory precautions gloves goggles and lab coat  

   Ensure work is conducted in a fume hood or wellventilated area  

 Storage  

   Store in a tightly sealed container in a cool dry and ventilated area  

   Protect from exposure to light and moisture

 Reactivity

 Functional Groups  

   Amino Group NH2 Highly reactive can participate in acylation alkylation or Schiff base formation  

   Ether Bond O Chemically stable under neutral conditions but may degrade under strong acidic or basic environments  

   Methoxy Group OCH3 Electrondonating enhances reactivity of the benzene ring in electrophilic substitution reactions

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